A NEW METHOD FOR THE PREPARATION OF HYDRAZIDES OF SUBSTITUTED GAMMA-HYDROXYBUTANOIC ACIDS

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Submitted: 2025-03-03; Published: 2025-03-03

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Abstract

A method providing a high yield (80–94%) for producing gamma-hydroxy-butanoic acids hydrazides by the interaction of various representatives of cyclic esters with 85% hydrazine hydrate has been elaborated. It has been established that the introduction of a gamma-hydroxypropyl residue into the hydrazides composition results in new biological properties.