Natural Sciences, Stomotology, 2026
ISSN: 1829-006X
EVALUATION OF BIOCERAMIC BASED SEALERS IN REGENERATIVE ENDODONTICS OF IMMATURE PERMANENT TEETH
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Submitted: 2026-04-08
© 2026 by author(s) and The Gufo Inc.
This work is licensed under Creative Commons Attribution–NonCommercial International License
(CC BY-NC 4.0).
Abstract
Background:In dentistry, bioceramics have found extensive application, especially in endodontics. The goal
of the current study was to assess the release of calcium ions (Ca2+) from apical plugs made of three distinct
bioceramic cements in immature teeth models with open apices.
Materials and Methods: Three groups of ten samples each were created from a total of thirty lower premolar teeth. Dia-Root Bio MTA is in Group I; MTA Fillapex is in Group II; and Biodentine is in Group III. Every sample was made to resemble teeth that were still developing and had open apices. At the exposed apex region, a 4 mm apical stopper was placed. On days 8, 16, and 30, calcium ion release was quantified with an atomic absorption spectrophotometer. Mann-Whitney U and Kruskal-Wallis tests were used to analyse the data at a significance level of P < 0.05.
Result:All groups demonstrated the highest levels of Ca2+ release till day 30th. Dia-Root Bio MTA showed the highest calcium ion release.
Conclusion:Dia-Root Bio MTA showed the highest calcium ion release followed by biodentine. The tested
materials can be used in regenerative endodontics for immature teeth development.