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Natural Sciences, Stomotology, 2026

COMPARATIVE EVALUATION OF BOVINE DERIVED XENOGRAFTS (BIO-OSS) AND DEMINERALIZED BONE MATRIX (OSSEOGRAFT) IN POST-EXTRACTION RIDGE PRESERVATION: A CBCT-GUIDED CLINICAL TRIAL

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Submitted: 2026-04-08
CC BY-NC 4.0 This work is licensed under Creative Commons Attribution–NonCommercial International License (CC BY-NC 4.0).

Abstract

Objective:To compare the effectiveness of Dimineralised Bone Matrix (Osseograft) and Bio-Oss in preserving
alveolar ridge dimensions following tooth extraction, using Cone Beam Computed Tomography (CBCT).
Materials and Methods: This randomized controlled trial included 30 extraction sockets. 20 Participants were
randomized into two groups: the Osseograft group and the Bio-Oss group. Following Atraumatic extraction, the
respective graft material was placed in the socket. Immediately after extraction, socket dimensions were measured
both bucco-lingually and mesio-dismally and then CBCT scans were conducted 3 months post-extraction. The
primary outcomes measured were changes in socket dimensions and horizontal bone width.
Results:Bio-Oss group showed statistically significant gains in both bucco-lingual (0.54 ± 0.20 mm) and mesiodistal (0.38 ± 0.15 mm) dimensions (p < 0.001), while Osseograft showed minimal change, significant only in
mesio-distal width (p = 0.033).
Conclusion: Bio-Oss showed superior performance in maintaining alveolar ridge dimensions compared to
Osseograft, suggesting it may be a more effective material for socket preservation. Further studies with larger
sample sizes and longer follow-up periods are recommended to validate these

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