THE EFFECTIVENESS OF TRIAMCINOLONE ACETONIDE (0.1%), AMLEXANOX (5%) AND CLOBETASOL PROPIONATE (0.05%) IN TREATING ORAL LICHEN PLANUS

Background: Oral lichen planus (OLP) is a potentially malignant mucocutaneous condition. The present research
done was to evaluate the efficiency of 0.1% triamcinolone acetonide, 0.05% clobetasol propionate, and 5%
amlexanox in treating OLP.
Methods: Three equal groups of sixty participants with OLP were treated with topical medications: 5% amlexanox
(Group III), 0.1% triamcinolone acetonide (Group II), and 0.05% clobetasol propionate (Group I). The visual
analogue scale (VAS) was used to evaluate the patients’ level of pain. On Days 1, 7, and 15 of the trial, their erosive
area and ulcerative lesion type were also assessed.
Results: In every investigated group, the VAS pain scale score decreased statistically significantly between Day 1
and Day 15. In comparison to the other two groups, Group B’s pain score was lower. Additionally, on the fifteenth
day, the erosive region on the left and right buccal mucosaon decreased with all three of the studied medications. In
comparison to 0.05% Clobetasol Propionate and 5% Amlexanox, triamcinolone acetonide (0.1%) was efficient in
improving the erosive lesions on the buccal mucosa on the right and left sides. Of the three groups, Group II had the
highest healing ratio (37 cases), Group I had the second-highest (32 cases), and Group III had the lowest (30 cases).
Conclusion: All medicines utilised in this trial –triamcinolone acetonide, clobetasolpropionate andamlexanox–were
beneficial in managing OLP patients; consequently, it can be considered as substitute.