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Natural Sciences, Stomotology, 2026

SURGICAL SUCCESS OF OVINE FORESTOMACH MATRIX IN THE MANAGEMENT OF PLEOMORPHIC ADENOMA OF HARD PALATE -CASE REPORT

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Submitted: 2026-04-08
CC BY-NC 4.0 This work is licensed under Creative Commons Attribution–NonCommercial International License (CC BY-NC 4.0).

Abstract

Pleomorphic adenoma is one of the common benign salivary gland tumors, occurring in the hard palate due to a high
density of minor salivary glands in this region. Surgical excision remains the mainstay of management; however,
defect site reconstruction following tumor excision poses a considerable challenge. The current case report presents
the first known use of the ovine forestomach matrix (OFM) for reconstructing the huge defect post excision. A 40-
year-old patient male presented with a progressively enlarging, painless swelling in the hard palate. Clinical
examination revealed a well-demarcated, fluctuant, non-tender lesion, crossing the midline, with a provisional
diagnosis of mucocele. Surgical excision was performed with wide margins to prevent risk of recurrence. The OFM
was employed as a biologic scaffold to facilitate wound healing and tissue regeneration. The patient demonstrated
exceptional healing with full mucosal coverage and no signs of infection or necrosis at the nine-month follow-up. The
successful integration of OFM in this case underscores its potential as a novel alternative adjuvant for reconstructing
oral and maxillofacial defects. This case sets a precedent encouraging further research to elucidate its long-term
efficacy and expand its application in maxillofacial surgical interventions.

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