Giant cell Fibroma of Lip: A case report

This case report describes a rare presentation of a giant cell fibroma (GCF) on the labial mucosa of a 24-year-old female. GCF is a benign fibrous connective tissue neoplasm, typically occurring on the gingiva and tongue. The patient presented with a small, pedunculated nodule on the lower lip. A clinical diagnosis of irritational fibroma was made, and excisional biopsy confirmed the presence of GCF based on histopathological examination, revealing characteristic stellate-shaped giant fibroblasts. The lesion was successfully excised with no recurrence at the one-year follow-up. This case highlights the importance of considering GCF in the differential diagnosis of benign fibrous lesions, even in atypical locations like the labial mucosa. Increased awareness and reporting of such cases can aid in better understanding the etiology and pathogenesis of GCF, ensuring accurate diagnosis and effective management.