Microflora changes of oral cav ity in pat ients with systemic scleroderma and Sjogren’s syndrome
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Microflora changes of oral cav ity in pat ients with systemic scleroderma and Sjogren’s syndrome Margarita Esayan
Oral microflora plays an important role in maintaining the patient’s health and protecting the body from pathogenic microflora, which is an etiological factor in many dental diseases, and can also lead to various pathological conditions, including immuno-inflammatory rheumatic diseases. One example is systemic scleroderma. Systemic scleroderma is a progressive polysyndromic immuno-inflammatory rheumatic disease with characteristic changes in the skin, musculoskeletal system, various internal organs and common vasospastic disorders, including Raynaud’s syndrome.
The aim of our study was to reveal the changes of oral microflora in patients with systemic scleroderma and Sjogren’s syndrome.
The study included 30 patients with systemic scleroderma and 25 patients with Sjogren’s syndrome. Bacteriological investigations of oral microflora were performed. The control group included 30 patients without rheumatologic pathology. To assess the intensity of caries and the level of oral hygiene, the caries intensity index and Oral Hygiene Indices-Simplified were determined.
The average caries intensity index in the systemic scleroderma group was 17.8±7.08 (very high caries intensity), the average Oral Hygiene Indices-Simplified was 2.27±0.7 (satisfactory hygiene); in the control group the average caries intensity index was 15.25±5.06 (high caries intensity), the average value of the Oral Hygiene Indices-Simplified - 2.01±0.6 (satisfactory hygiene). According to the results of a microbiological study in patients with systemic scleroderma, in 21.95% of cases pathogenic Staphylococcus aureus was detected in an etiologically significant amount >106 CFU/ml, in the Sjogren’s syndrome group it was detected in 28.36% of cases, in the
control group – in 7.81% of cases. Candida albicans in an etiologically significant amount >106 CFU/ml was detected in 20.73% of cases in the systemic scleroderma group, in 20.9% of the Sjogren’s syndrome group and in 9.38% of cases in the control group. Conclusions: high level of caries intensity and an unsatisfactory level of oral hygiene were detected. Dysbiotic shift of 3 degrees in patients with systemic scleroderma and Sjogren’s syndrome was observed.
DOI: https://ysmu.am/v2/wp-content/uploads/2023/05/b18687cf-1.pdf The New Armenian Medical Journal Vol.15 (2021), Nо 1 4-9
