Evaluation of the efficacy of platelet rich fibrin on the following complicat ions after surgical extraction of the lower third molar in smoker pat ients (Randomized clinical trial)
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Evaluation of the efficacy of platelet rich fibrin on the following complicat ions after surgical extraction of the lower third molar in smoker pat ients (Randomized clinical trial) Zaven Garabed
Much scientific evidence indicates the importance of the use of platelet-rich fibrin in the management of the healing of oral soft and bony tissues. The effectiveness of this substance is due to the growth factors and effective properties it contains in improving the healing and healing phase and relieving pain after surgery. Since the surgical extraction of the impacted third molars is one of the most common operations within the oral and maxillofacial surgeon’s clinic, pain, and postoperative alveolitis are the most annoying complications for the patient.
Present study aimed to assess the effect of platelet-rich fibrin after topical application in the cavity of the socket of the impacted lower third molar surgical extractions in smokers.
Material and methods: 15 smoker patients who needed to have the lower third molars extracted under local anesthesia (n = 30) randomized with an X, O method for one of the two incisions. The two parts of the study group are one in which platelet rich fibrin is applied within the socket cavity just before suturing and another where nothing is applied.
Postoperative pain was assessed using a visual analogue scale scale on days 1, 2, 3, 5, and 7, and by the patient’s dose of analgesic. The rate of alveolitis was evaluated, and then the variables were studied by comparison between the study group and the control group.
Results: In the study group, the visual analogue scale values were lower with a statistically significant difference compared with them in the control group on the first, second and third days after surgery (P <0.05).
Conclusion: This study indicated that the topical application of platelet-rich fibrin within the socket of the impacted lower third molar after its extraction in smokers is an effective method in relieving symptoms following surgical extractions and that it contributed positively to reducing the incidence of alveolitis.
DOI: https://ysmu.am/v2/wp-content/uploads/2023/05/7908e20c-1.pdf The New Armenian Medical Journal Vol.15 (2021), Nо 1 44-52