Mineralization of bones in pat ients with coronary heart disease complicated by chronic heart failure and pharmacologic management

Our study aims to investigate the effect of combined calcium with vitamin D3 supplement called “calcemin-advance” and calcitonin in the prophylaxis and treatment of osteopenia and osteoporosis in patients with coronary heart disease complicated by chronic heart failure with the establishment of their influence on the bone mineral density.
Totally 59 patients with coronary heart disease complicated by chronic heart failure. Interventions: The physical examination findings, Dual-energy X-ray absorptiometry findings and treatment results were assessed.
The results of the calcemin-advance usage in patients with osteopenic changes showed a positive dynamics of the studied parameters, both in the lumbar spine and in the femoral bone. In patients with osteoporosis the usage of osteoprotective therapy (calcemin-advance+miacalcic) contributed to the increasing of bone mineral density in lumbar spine and in the femoral bone vs patients who received only combined calcium with vitamin D3 supplement.
Our results suggest that bone density screening could be recommended in patients with prevalent chronic heart failure. Moreover, the results of our investigation substantiate the necessity and effectiveness of osteoprotective therapy in patients with chronic heart failure with osteoporosis by calcitonin (miacalcic), in combination with combined calcium and vitamin D3 supplement (calcemin-advance), and by only calcemin-advance in patients with chronic heart failure and osteopenia.