Peculiarities of the realization of psychosomatic disorders in patients with gastroesophageal reflux disease with concomitant diabetes mellitus type 2 in young people

Objective. To study the peculiarities of the realization of psychosomatic disorders in patients with gastroesophageal reflux disease with concomitant diabetes mellitus type 2 and to develop methods for their correction.
Materials and methods. In order to obtain the results we conducted a study of two groups of patients suffering from GERD with concomitant mild to moderate diabetes mellitus type 2 and isolated GERD. The survey program included: determining the degree of carbohydrate metabolism compensation; state of aggression factor. For the evaluation of gastric secretion we used the daily pH-metry. Also, all patients underwent an ultrasound investigation with water load. Indices of oxidative stress were assessed by the diameter of the celiac trunk and blood flow velocity in it.
Psychosomatic disorders and quality of life of the patients were estimated by conducting a survey using unified questionnaires.
Results. We established that in patients with GERD with concomitant diabetes mellitus there was a clear tendency towards stabilization of the glycemic profile. In patients of both groups, episodes of heartburn, frequency and intensity of belching, and dyspeptic phenomena decreased.
We found that, after a 4-week course of therapy, oxidative stress levels in patients of both treatment groups decreased. The findings suggest that psychosomatic disorders are factors that not only make the course of GERD and DM type 2 more difficult, but also take a direct part in the formation of GERD itself in DM type 2.
The results of our studies also clearly indicate that the additional assigning of actovegin in the general scheme of treatment for patients with DM type 2 with concomitant GERD has an evident positive effect on the reduction of the onset of clinical remission of both DM type 2 and concomitant GERD.
Conclusions. The inclusion of actovegin in the general treatment scheme of patients with GERD and DM contributes to a significant reduction in the recrudescence period of both DM and concomitant GERD.