This work is licensed under Creative Commons Attribution–NonCommercial International License
(CC BY-NC 4.0).
Orthodontic treatment poses challenges to maintaining periodontal health due to increased plaque accumulation, gingival inflammation, and enamel demineralization associated with fixed appliances. Conventional chemical mouthwashes like chlorhexidine are effective but often cause undesirable side effects such as staining and mucosal irritation. In contrast, herbal and phytochemical-based mouthwashes offer antimicrobial, anti-inflammatory, and antioxidant benefits with minimal adverse effects. This review explores the role of plant-based mouthwashes— including green tea, neem, aloe vera, triphala, curcumin, and clove—in improving periodontal outcomes among orthodontic patients. These natural formulations inhibit pathogenic biofilms, reduce inflammatory mediators, and support tissue healing while preserving oral microbial balance. Comparative analyses reveal that many herbal mouthwashes perform as effectively as chlorhexidine in reducing plaque and gingival inflammation. Their favorable safety profile and holistic action make them a promising adjunct in long-term orthodontic care. Future research should focus on optimizing delivery systems and validating long-term efficacy through clinical trials.