Site logo

ANTIOXIDANT DRUGS FROM HYDRO-ETHANOLIC FLORAL EXTRACTS OF IMPATIENS BALSAMINA L.: AN IN VITRO ANALYSIS

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

CC BY-NC 4.0 This work is licensed under Creative Commons Attribution–NonCommercial International License (CC BY-NC 4.0).

Abstract

Oxidative stress or oxidative cell damage may lead to various systemic or chronic diseases including cancer. Therefore, there is a need to prevent the cells from oxidative stress resulting prevention of disease.
As a consequence of this, our study investigated the anti-oxidant property of hydroethanolic Impatiens balsamina L. flower extracts using various antioxidant assays such as 2,2-diphenyl1-picrylhydrazyl free radical scavenging assay, 2,2′-Azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) scavenging assay, catalase assay, hydroxyl radical scavenging activity, and nitric oxide scavenging activity.
The results revealed the potent antioxidant activity through 2,2-diphenyl-1-picrylhydrazyl, 2,2′-Azino-bis (3-ethylbenzthiazoline-6-sulfonic acid), catalase, hydrogen peroxide, and nitric oxide scavenging activities. The extract showed efficient inhibitions at 100 µg/ml as 56%, 69%, 67%, 56%, and 59% for 2,2-diphenyl-1-picrylhydrazyl, 2,2′-Azino-bis (3-ethylbenzthiazoline-6-sulfonic acid), catalase, hydrogen peroxide, and nitric oxide, respectively.
Overall, hydroethanolic I. balsamina flower extracts had potent antioxidant activity that could be used as a therapeutic agent in the management of oxidative stress.

Subscribe to TheGufo Newsletter​