Natural Sciences, Stomotology, 2026
ISSN: 1829-006X
Boosting Gum Health: CoQ10, Beta-Carotene and Neem vs. Chlorhexidine Gel in Periodontal Therapy – A Pilot Study
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Submitted: 2026-04-08
© 2026 by author(s) and The Gufo Inc.
This work is licensed under Creative Commons Attribution–NonCommercial International License
(CC BY-NC 4.0).
Abstract
Background: Periodontal disease is primarily caused by dental plaque, necessitating effective plaque control to prevent and manage the condition. Chemical plaque control can be used as an adjunct to mechanical methods. Chlorhexidine (CHX) is widely used for its antimicrobial properties, while Coenzyme Q10 (CoQ10) is an antioxidant with potential benefits in periodontal therapy.
Objective: The study aims to evaluate and compare the clinical efficacy of 1% CHX gel and CoQ10 gel in patients with
periodontal pockets.
Materials and Methods: A total of 10 patients with Probing Pocket Depth (PPD) of 4-6 mm were selected. Post Scaling
and Root Planing (SRP), Group A received 1% CHX gel and Group B received CoQ10 gel, to be applied twice daily.
Clinical parameters, including Gingival Index (GI) and PPD, were recorded at baseline, 21 days and 45 days.
Results: Both groups showed a statistically significant reduction in PPD over 45 days. However, intergroup comparison revealed no significant difference between the two treatments.
Conclusion: Coenzyme Q10 demonstrated results comparable to Chlorhexidine in treating periodontal pockets with the added advantage of no known side effects. This suggests that Coenzyme Q10 could serve as a safe and effective
alternative for long-term periodontal therapy.