Natural Sciences, Stomotology, 2026
ISSN: 1829-006X
CHOROIDAL MELANOMA IN PATIENT WITH VITILIGO: CASE REPORT
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Submitted: 2026-04-08
© 2026 by author(s) and The Gufo Inc.
This work is licensed under Creative Commons Attribution–NonCommercial International License
(CC BY-NC 4.0).
Abstract
Choroidal melanoma is the most common primary intraocular malignancy in adults , arising from melanocytes within
the uveal tract. Vitiligo is an autoimmune skin disorder characterized by depigmentation due to melanocyte destruction
. While vitiligo has been associated with a decreased incidence of cutaneous melanoma , reports of uveal melanoma in
patients with vitiligo remain rare . This article presents a case of choroidal melanoma in a patient with a known history
of more than 20 years vitiligo, explores the possible immunological implications of this association and shows the
ophthalmological management of such a rare case.