Abstract

Choroidal melanoma is the most common primary intraocular malignancy in adults , arising from melanocytes within the uveal tract. Vitiligo is an autoimmune skin disorder characterized by depigmentation due to melanocyte destruction . While vitiligo has been associated with a decreased incidence of cutaneous melanoma , reports of uveal melanoma in patients with vitiligo remain rare . This article presents a case of choroidal melanoma in a patient with a known history of more than 20 years vitiligo, explores the possible immunological implications of this association and shows the ophthalmological management of such a rare case.

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