Bulletin of Stomatology and Maxillofacial Surgery
ISSN 1829-006X
2025; 533–540
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COMPARATIVE CLINICAL AND MICROBIOLOGICAL EFFECTS OF 0.12% CHLORHEXIDINE ON PMMA VERSUS POLYAMIDE DENTURE BASES: A CONTROLLED STUDY ANCHORED TO ISO 20795-1

Omar Al-Fatyan*, Intisar Farhood, Tasneem Assi

College of Dentistry, University Al Maarif, Al Anbar, Iraq · Al-Hikma University College, Baghdad, Iraq · Al-Yarmok University College, Department of Dentistry, Baghdad, Iraq

Received: 2026-04-08 · Published: 2025-11-29

© 2025 The Author(s) and the original publisher.

CC BY-NC 4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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Original title
COMPARATIVE CLINICAL AND MICROBIOLOGICAL EFFECTS OF 0.12% CHLORHEXIDINE ON PMMA VERSUS POLYAMIDE DENTURE BASES: A CONTROLLED STUDY ANCHORED TO ISO 20795-1
Authors
Omar Al-Fatyan, Intisar Farhood, Tasneem Assi
Source journal
Bulletin of Stomatology and Maxillofacial Surgery
Published
2025-11-29
Licence
Creative Commons Attribution-NonCommercial 4.0 International
Original
https://doi.org/10.58240/1829006X-2025.21.10-533

Abstract

Objective: To compare the clinical, microbiological, immunological, and ISO-aligned laboratory effects of a 14-day 0.12% chlorhexidine (CHX) regimen on PMMA versus polyamide denture bases. Methods: Forty edentulous participants were allocated to PMMA (n=20) or polyamide (n=20). Primary outcomes were. Budtz-Jørgensen denture plaque index and Newton’s classification; secondary outcomes included PI, GI, GCF cytokines (IL-6, TNF-α), Candida CFU/cm², and ISO 20795-1 laboratory metrics (Ra, ΔE, flexural properties, sorption/solubility). Results: Both materials demonstrated significant clinical and microbiological improvements after CHX, whereas PMMA exhibited greater surface and color changes; polyamide showed superior esthetic stability. Conclusions: CHX is an effective short-term adjunct regardless of base material; material-dependent surface/esthetics effects should guide maintenance protocols.
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