Natural Sciences, Stomotology, 2026
ISSN: 1829-006X
COMPARATIVE EVALUATION OF ENDOGLIN EXPRESSION IN AMELOBLASTOMA, ODONTOGENIC KERATOCYST, AND DENTIGEROUS CYST: AN INSTITUTIONAL STUDY WITH A COMPREHENSIVE LITERATURE REVIEW
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Submitted: 2026-04-08
© 2026 by author(s) and The Gufo Inc.
This work is licensed under Creative Commons Attribution–NonCommercial International License
(CC BY-NC 4.0).
Abstract
Background: Odontogenic cysts and tumors are common areas of interest for Oral and maxillofacial surgeons and
pathologists with their unique characteristics and prevalence. Angiogenesis has recently stimulated greater interest in
lesion dynamics as vascularity provides nutrient supply responsible for proliferation activities.
Objectives: In order to comprehend its function in the biological behavior of these lesions, the study seeks to evaluate
and compare the expression of the putative angiogenic marker CD105 in dentigerous cysts, odontogenic keratocysts,
and ameloblastomas.
Methods: A total of N=36 histopathologically diagnosed cases of OKC, DC and Ameloblastoma were selected with
control (Angiomatous Granuloma). Immunohistochemistry was performed using a CD105 marker.
Result: Angiogenesis was found to be increased in ameloblastoma followed by OKC and Dentigerous cyst and the
results were statistically significant in comparison with that of the control.