Bulletin of Stomatology and Maxillofacial Surgery
ISSN 1829-006X
2025; 454–465
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COMPARATIVE EVALUATION OF ENDOGLIN EXPRESSION IN AMELOBLASTOMA, ODONTOGENIC KERATOCYST, AND DENTIGEROUS CYST: AN INSTITUTIONAL STUDY WITH A COMPREHENSIVE LITERATURE REVIEW

Nausathkhan Ubayathulla*, M.R. Muthusekar, Abilasha Ramasubramanian, Kavya Dharmaraj

Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India, Department of Oral and Maxillofacial Surgery, EHS, Fujairah Specialized Dental Center and Hospital, Fujairah, UAE · Department of Oral Surgery, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India · Department of Oral and Maxillofacial Pathology, Saveetha Dental College and Research Institute, Saveetha University, SIMATS, Chennai, Tamil Nadu, Indi

Received: 2026-04-08 · Published: 2025-09-20

© 2025 The Author(s) and the original publisher.

CC BY-NC 4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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Original title
COMPARATIVE EVALUATION OF ENDOGLIN EXPRESSION IN AMELOBLASTOMA, ODONTOGENIC KERATOCYST, AND DENTIGEROUS CYST: AN INSTITUTIONAL STUDY WITH A COMPREHENSIVE LITERATURE REVIEW
Authors
Nausathkhan Ubayathulla, M.R. Muthusekar, Abilasha Ramasubramanian, Kavya Dharmaraj
Source journal
Bulletin of Stomatology and Maxillofacial Surgery
Published
2025-09-20
Licence
Creative Commons Attribution-NonCommercial 4.0 International
Original
https://doi.org/10.58240/1829006X-2025.21.8-454

Abstract

Background: Odontogenic cysts and tumors are common areas of interest for Oral and maxillofacial surgeons and pathologists with their unique characteristics and prevalence. Angiogenesis has recently stimulated greater interest in lesion dynamics as vascularity provides nutrient supply responsible for proliferation activities. Objectives: In order to comprehend its function in the biological behavior of these lesions, the study seeks to evaluate and compare the expression of the putative angiogenic marker CD105 in dentigerous cysts, odontogenic keratocysts, and ameloblastomas. Methods: A total of N=36 histopathologically diagnosed cases of OKC, DC and Ameloblastoma were selected with control (Angiomatous Granuloma). Immunohistochemistry was performed using a CD105 marker. Result: Angiogenesis was found to be increased in ameloblastoma followed by OKC and Dentigerous cyst and the results were statistically significant in comparison with that of the control.
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