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Natural Sciences, Stomotology, 2026

COMPARISON OF PEDIATRIC SYRUPS ON MICROHARDNESS AND SURFACE ROUGHNESS OF DIFFERENT RESIN RESTORATIONS: AN IN-VITRO STUDY

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Submitted: 2026-04-08
CC BY-NC 4.0 This work is licensed under Creative Commons Attribution–NonCommercial International License (CC BY-NC 4.0).

Abstract

Objective: The study objective was to compare the alterations in microhardness and surface roughness (SR) of three
distinct resin-based restorations commonly employed in pediatric dentistry under continuous exposure (at baseline, 7, 14, and 21 days) to frequently utilized pediatric syrups.
Materials and methods: In this in vitro study, three pediatric syrups used as immersion agents were
amoxicillin+clavulanic acid, paracetamol, and haematinic syrup. The materials evaluated were Compomer,
Microhybrid, and Nanofill composite resin restorations. The study included 180 caries-free, non-restored deciduous
molar teeth without developmental anomalies that were extracted due to pre-shedding mobility. The surface
microhardness and SR were measured with a Vickers microhardness durometer and a contact profilometer
respectively. ANOVA was used for intra- and inter-group data comparisons at a 5% significance level using SPSS
software.
Results: On day 21, the antibiotic-micro-hybrid group had the highest microhardness (52.95±0.62). The compomerhematinic group had the lowest microhardness (13.22±0.33). The SR of the compomer-paracetamol group was the highest (1.47±0.43), while the micro-hybrid-antibiotic group had the lowest (0.83±0.07). Intragroup comparisons showed significant differences (p<0.01), showing a decrease in material microhardness with an increased exposure period. The compomer subgroups exposed to paracetamol and haematinic and the nanofill composite exposed to haematinic syrup exhibited a significant difference (p<0.01).
Conclusion: The microhardness of compomer-paracetamol, compomer-antibiotic, and nanofill-paracetamol
subgroups increased over the study period. The SR of the compomer and nanofill materials treated with haematinic
syrup and compomer-paracetamol subgroup increased considerably.

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