Purpose of research is the definition of influence of ozono -air mixture, gained with the help of ultraviolet light, indicators of local immunity in patients with bisphosphonate osteonecrosis of jaws.
First group of research includid 38 patients with bisphosphonate osteonecrosis of jaws in the age from 32 to 78 years. To the Patients of this group have been conducted treatment, including monthly courses of ozontherapie in the area of osteonecrosis, consisting of 10 everyday procedures (from 2 to 10).
“Сontrol” group of research included 22 patients with bisphosphonate osteonecrosis of jaws in the age from 49 to 76 years, which were conducted treatment of osteonecrosis, without ozontherapie.
The analysis of indicators of targeted immunity to all patients was conducted before, after treatment, at occurrence at a radiological research of signs of sequestration.
The analysis of indicators of local immunity to the patients after treatment with using local ozontherapie showed strong positive dynamics, which is characterized by increase in activity phagocytosis in 1.2 times. Also it showed increase in quantity of late neutrophils (EN-PO) in 1.2 times (p<0.05).
The obtained data confirm increase in products of a S-component ephythelial cells of a mucous membrane of an oral cavity (S-IgA/IgA) and strengthening of a protective role of S-IGA (S-IgA/IgG).
As a result of carried out treatment to 20 patient 1 group (46.7%) has been formed sequesters.
At execution of analysis of ratings local immunity at the patients of the second group decrease of the content 1.2 times protective S-IgA in the saliva in as compared with norm was preserved (p <0.05) that points to decrease of protective role S-IgA in the oral cavity.
As well marginal improvement of activity and rate of phagocytosis is revealed, however their decrease is preserved regarding norm to 1.22 times (p <0.05) and 1.3 times respectively (p <0.05).
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Medicine
, 2025, Issue 1, pp. 1–10
ISSN Online: 0000-0000
DOI:
10.xxxx/example-doi