Natural Sciences, Stomotology, 2026
ISSN: 1829-006X
EXTRANODAL ORBITAL HISTIOCYTOSIS IN ROSAI-DORFMAN DISEASE: A CASE REPORT AND LITERATURE REVIEW
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Submitted: 2026-04-10
© 2026 by author(s) and The Gufo Inc.
This work is licensed under Creative Commons Attribution–NonCommercial International License
(CC BY-NC 4.0).
Abstract
Rosai-Dorfman disease (RDD) is a rare disorder characterized by sinus histiocytosis with massive lymphadenopathy.
It most commonly affects young males. Most patients were presented with enlarged cervical lymph nodes, pyrexia and
fatigue. It primarily happened in the lymph nodes. Extranodal disorder can be present in eye, salivary gland,
respiratory tract, skin, skeleton, brain layers and testis. A 14-year old male presented with proptosis associated with
throbbing pain. MRI and DWI MRI,were done. MRI and DWI revealed a diffusely infiltrative orbital soft tissue mass
with eyelid swelling.