Natural Sciences, Stomotology, 2026
ISSN: 1829-006X
HISTOPATHOLOGYC AND DERMOSCOPIC FINDINGS OF SUBACUTE CUTANEOUS LUPUS ERYTHEMATOSUS
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Submitted: 2026-04-08
© 2026 by author(s) and The Gufo Inc.
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(CC BY-NC 4.0).
Abstract
The relevance, pathogenesis, classification, and clinical characteristics of a rare disease-subacute cutaneous lupus
erythematosus-are presented.
A clinical case in a 60-year-old woman without signs of organ pathology is also described.
A dermatoscopic examination was performed. In the affected areas on the facial skin, twisted, short linear,
occasionally branching, unfocused vessels, predominantly bright red in color, forming incomplete polygonal
structures, were identified. In the affected areas on the skin of the extremities, irregularly arranged dotted-granular
and twisted short linear vessels of dull red color were visualized, along with structureless zones of varying degrees
of discoloration, exhibiting whitish-orange shades.
Pathomorphologically, the process is characterized by mild focal hyperkeratosis, vacuolar degeneration of the basal
layer of the epidermis, a mildly expressed perivascular lymphohistiocytic inflammatory infiltrate, as well as a
moderately expressed periadnexal (perieccrine) lymphohistiocytic inflammatory infiltrate.
Based on the medical history, clinical presentation, and the results of dermoscopic and histological examinations,
the diagnosis of psoriasiform subacute cutaneous lupus erythematosus was established.