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Natural Sciences, Stomotology, 2026
ISSN: 1829-006X

INTEGRATING 3D BIO PRINTING AND PERSONALIZED MEDICINE WITH SCAFFOLD CONSTRUCTS – THE FUTURE OF ORAL CANCER TREATMENT

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Submitted: 2026-04-08
CC BY-NC 4.0 This work is licensed under Creative Commons Attribution–NonCommercial International License (CC BY-NC 4.0).

Abstract

The treatment of oral cancer is changing due to the introduction of 3D bioprinting technology, creating personalized models for drug testing and therapy development. Through the precise recreation of TMEs using cells derived from patients, 3D bioprinted models allow for accurate drug screening and personalized treatment approaches, which could improve effectiveness and minimize adverse reactions. Scaffold structures, essential to this method, provide support for delivering drugs to specific targets and for tissue engineering, enhancing drug distribution and assisting with tissue regeneration after surgery. Although there are hurdles in standardizing and getting regulatoryapproval, combining 3D bioprinting with personalized medicine and scaffold constructs shows potential for enhancing oral cancer treatment with more efficient and customized therapies.

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