PERIODONTITIS AND UROLOGIC CANCERS: A NARRATIVE REVIEW OF POTENTIAL RISK CONNECTIONS

Urologic cancers, including prostate, bladder, and kidney cancers, represent a major global health burden with complex and multifactorial etiologies. An infectious inflammatory illness called periodontitis has been increasingly implicated in systemic conditions like cancer Mechanisms involving oxidative stress, disruption of the immune system, systemic inflammation, and body microbiome modulation are likely accountable for these correlations. We detail recently established correlations
among urologic cancers and periodontitis, with emphasis upon systemic inflammation as an important common pathway, in this review. The correlation between oral diseases and cancer risk suggests multidisciplinary research potentially could define these correlations and provide focused therapies Clinically, periodontal evaluation inclusion in general cancer risk profiling potentially could deliver new directions in patient care prevention.