Bulletin of Stomatology and Maxillofacial Surgery
ISSN 1829-006X
2025; 469–474
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PREVALENCE OF GORLIN-GOLTZ SYNDROME AMONG PATIENTS WITH ODONTOGENIC KERATOCYSTS- A RETROSPECTIVE STUDY.

Shanthi Viswanathan*

Tamil Nadu Government Dental College and Hospital Chennai, Tamil Nadu, India

Received: 2026-04-08 · Published: 2025-11-20

© 2025 The Author(s) and the original publisher.

CC BY-NC 4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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Original title
PREVALENCE OF GORLIN-GOLTZ SYNDROME AMONG PATIENTS WITH ODONTOGENIC KERATOCYSTS- A RETROSPECTIVE STUDY.
Author
Shanthi Viswanathan
Source journal
Bulletin of Stomatology and Maxillofacial Surgery
Published
2025-11-20
Licence
Creative Commons Attribution-NonCommercial 4.0 International
Original
https://doi.org/10.58240/1829006X-2025.21.10-469

Abstract

Background: Odontogenic keratocyst (OKC) is a distinct developmental odontogenic cyst of the jaws known for its characteristic behavior. It has a significant association with Gorlin-Goltz syndrome, which is an autosomal dominant genetic disorder. This study aims to assess the association between OKC and Gorlin-Goltz syndrome and to estimate the prevalence of the syndrome in patients with OKC. Methods: A retrospective study was conducted among patients who reported to the Department of Oral Pathology at Tamil Nadu Government Dental College and Hospital, Chennai over a 15-year period (2018-2022). Patients with a histopathological diagnosis of OKC were included. Clinical, radiographic findings along with histopathological diagnosis were recorded. Based on the available data, the patients were diagnosed as having Gorlin-Goltz syndrome or not based on the criteria available for identifying the syndrome. Results: The study population consisted of 120 patients, with a male-to-female ratio of 1.26:1. The mean age at diagnosis of OKC was 40 years. Among the patients with odontogenic keratocysts, 6.6% exhibited clinical features consistent with Goltz-Gorlin syndrome. Conclusion: The findings indicate that the diagnostic criteria for Gorlin-Goltz syndrome may be expressed differently across various demographic groups.
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