The effect of Vaginal Bacillus (Lactobacillus acidophilus) Towards Candida spp. Isolated from Women with Candidiasis
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The effect of Vaginal Bacillus (Lactobacillus acidophilus) Towards Candida spp. Isolated from Women with Candidiasis Jawad Alzaidi
The aim of the current study was to investigate the isolation of vaginal Lactobacilli (L. acidophilus) and vaginal Candida from women complaining of vaginal candidiasis, as well as study the antagonistic effect between these microorganisms. L. acidophilus bacteria and vaginal Candida yeast were isolated from one hundred High Vaginal Swab .Samples from patients complaining candidiasis who consulted the obstetrics and gynecology consultant at two main hospitals in Mosul city. This study showed a significant prevalence of 76 yeast isolates 76%, out of a total of 100 HVS samples. The isolated Candida strains were further identified by the routine microbiological procedure as C. albicans, C. femata, C. glabrata, C. tropicalis, C. parapsilosis, C. krusei and C. lusitaniae isolated by proportions 53.94%, 23.68%, 10.53%, 5.26%, 1.33%, 2.63%,
2.63% respectively. Also the strains of Lactobacillus were further identified by the routine microbiological procedure and by API 50 CHL systems as L. acidophilus (53.4%), L. gasseri (22.7%), L. vaginalis (13.6%), L. casei (5.6%), and L. crispatus (4.4%). The results of the antagonism test indicated that vaginal L. acidophilus strains had no ability to inhibit C. albicans, the causative organism of vaginal candidiasis, but they showed a high ability to inhibit C. femata, and demonstrated clear inhibitory activity towards C. glabrata, and C. tropicalis. Also, they showed inhibitory capacity towards C. parapsilosis, but showed a lower inhibitory effect against C.
krusei and C. lusitaniae. The causes and conditions leading to such results were discussed and some suggestions that may be due to the possibility of exploiting the phenomenon of antagonism between the two types of organisms have been set to reduce the incidence of vaginal candidiasis. In vitro antimicrobial activity of the vaginal lactobacilli (L. acidophilus) on Candida, suggesting that they could be a promising candidate for protection against vaginal candidiasis.
DOI: https://ysmu.am/v2/wp-content/uploads/2023/05/944c07b9-1.pdf The New Armenian Medical Journal Vol.15 (2021), Nо 3 77-83
