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A NEW METHOD FOR THE PREPARATION OF HYDRAZIDES OF SUBSTITUTED GAMMA-HYDROXYBUTANOIC ACIDS

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

CC BY-NC 4.0 This work is licensed under Creative Commons Attribution–NonCommercial International License (CC BY-NC 4.0).

Abstract

A method providing a high yield (80–94%) for producing gamma-hydroxy-butanoic acids hydrazides by the interaction of various representatives of cyclic esters with 85% hydrazine hydrate has been elaborated. It has been established that the introduction of a gamma-hydroxypropyl residue into the hydrazides composition results in new biological properties.

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