Site logo
Natural Science, Biology, 2024, 14, 67–75
DOI: 10.xxxx/example-doi Special Issue 1(2), 2022 186–1928

SYNTHESIS OF NEW 3-CYANOPYRIDINE-2(1H)-ONES WITH UNSATURATED SUBSTITUENTS AT C-4

Received N/A; revised N/A; accepted N/A
CC BY-NC 4.0 This work is licensed under Creative Commons Attribution–NonCommercial International License (CC BY-NC 4.0).

3-Cyanopyridine-2(1H)-ones containing unsaturated substituents at the position C-4 and various substituents at N-1 of the ring have been synthesized as new potential bioactive compounds by interaction of ethyl ylidene cyanoacetate with dimethylformamide dimethyl acetal, and simultaneous reamination-cyclization of obtained derivatives with amines to targeted 3-cyanopyridine-2(1H)-ones.

Subscribe to TheGufo Newsletter​