2013; Chemical and Biological Sciences 47 (3 (232): 28–32
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ADENOSINE DEAMINASE ACTIVITY IN SYNOVIAL FLUID AT ARTHRITIS

Ara Antonyan*

Received: 2025-03-12 · Published: 2013-11-15

© 2013 The Author(s) and the original publisher.

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Original title
ADENOSINE DEAMINASE ACTIVITY IN SYNOVIAL FLUID AT ARTHRITIS
Author
Ara Antonyan
Published
2013-11-15
Licence
as stated by the publisher

Abstract

It was found that the levels of Adenosine deaminase activity in joint effusions of patients with rheumatoid arthritis and osteoarthritis differ significantly (p < 0.0001). To differentiate the arthritis of these two etiologies, the cutoff value of the enzyme activity in synovial fluid was evaluated as 12 IU/L with sensitivity 0.96, specificity 0.89 and diagnosis efficiency 0.93. Based on this observation, we can offer using in clinics of Armenia the Adenosine deaminase activity in synovial fluid for quick diagnosis of rheumatoid arthritis as a sensitive, specific, low-cost and technically convenient test.
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