THE NEW ARMENIAN MEDICAL JOURNAL Volume17 (2023), Issue 2
2023; 118–126
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ANTIMICROBIAL ACTIVITY OF AMARANTHUS CAUDATUS EXTRACT AGAINST MULTIDRUG RESISTANT ACINETOBACTER BAUMANNII AND KLEBSIELLA PNEUMONIAE

Bari Nadeem*, M.A. Alfaki

Department of Basic Medical Sciences, College of Medicine, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.

Received: 2025-07-24 · Published: 2023-10-01

© 2023 The Author(s) and the original publisher.

Licence: as stated by the publisher.
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Original title
ANTIMICROBIAL ACTIVITY OF AMARANTHUS CAUDATUS EXTRACT AGAINST MULTIDRUG RESISTANT ACINETOBACTER BAUMANNII AND KLEBSIELLA PNEUMONIAE
Authors
Bari Nadeem, M.A. Alfaki
Source journal
THE NEW ARMENIAN MEDICAL JOURNAL Volume17 (2023), Issue 2
Published
2023-10-01
Licence
as stated by the publisher
Original
https://doi.org/10.56936/10.56936/18290825-2023.17.2-118

Abstract

Nowadays, new and effective antifungal or antimicrobial medications are required due to the rise of drug-resistant organisms. Most people have thought about using medicinal herbs to naturally treat illnesses with bacterial origins. In this study, two multidrug resistant (MDR) bacteria were used as in vitro models to compare the effects of antimicrobial medicinal plant extracts. The antibacterial effects of a Amaranthus caudatus seed extract was elicited by different solvents on Acinetobacter baumannii and Klebsiella pneumoniae were examined in this experimental study using the disc diffusion assay and the minimum inhibitory concentration (MIC) method. GC-MS analysis identified several antibacterial compounds, viz. hexadecane, dodecane, undecane, heptacosane, etc. The extracts’ effectiveness was examined through their anti-bacterial and antioxidant activity. Plant extracts with various compounds demonstrated antibacterial activity in the current study. They can therefore serve as a new source of antibacterial compounds.
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