Combination of type 2 diabetes mellitus with hypertension accelerates the development of diastolic heart dysfunction and myocardial remodeling. In turn, a change in the geometry of the heart is associated with the accelerated development of heart failure.
The aim of this study was to examine the parameters of remodeling and the diastolic function of the myocardium in patients suffering from type 2 diabetes mellitus with moderate hypertension.
Two groups of patients matched for sex and age were examined. Group I included 256 patients with type 2 diabetes mellitus and moderate hypertension; Group II consisted of 148 patients with grade II hypertension. To evaluate the remodeling of the myocardium and diastolic function, all patients underwent echocardiography using a Philips EPIQ machine in standard B-mode and M-modes.
As a result of the study, it was revealed that when type 2 diabetes mellitus is combined with moderate hypertension, 91% of patients develop left ventricular hypertrophy, and hypertrophic forms of left ventricular remodeling are observed in 83% of patients (hypertrophic and eccentric hypertrophy). The patients with moderate hypertension in combination with diabetes mellitus develop diastolic dysfunction in 88% of cases, its rigid type prevailing. The most sensitive method for detecting early signs of diastolic myocardial dysfunction in patients with diabetes mellitus and hypertension is tissue Doppler echocardiography.
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