Background: Radicular cysts are the most common inflammatory odontogenic cysts, accounting for 52–
68% of all jaw cysts. They arise from pulpal necrosis–induced inflammation involving the epithelial rests of
Malassez.
Aim: To present a comprehensive clinicopathological analysis of 200 surgically confirmed radicular cysts
with complete clinical, radiographic, and histopathological records.
Materials and Methods: Data from 200 patients were evaluated for demographics, clinical features,
radiographic characteristics, histopathology, treatment modalities, and recurrence patterns. Findings were
compared with previous studies for correlation.
Results: Most patients were males (64%) aged 21–40 years. Maxillary involvement (59%) and anterior
region lesions (67%) predominated. Clinically, 58% of cases were symptomatic. Radiographically, all lesions
were well-defined unilocular radiolucencies, mostly 1–2 cm in size; 23% showed root resorption and 19%
caused displacement. Histologically, lesions predominantly exhibited non-keratinized stratified squamous
epithelium with chronic inflammation, cholesterol clefts, Rushton bodies, and hyaline bodies. Enucleation
was the main treatment (89%), with a low recurrence rate (2%).
Conclusion: The study confirms the predictable clinical, radiographic, and histopathological patterns of
radicular cysts while highlighting occasional variations such as calcifications or exogenous materials.
Integrated evaluation is essential for accurate diagnosis and proper management.
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