Bulletin of Stomatology and Maxillofacial Surgery
ISSN 1829-006X
2025; 408–412
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COMPARING THE LOCAL ANAESTHETIC EFFICACY DURING THE EXTRACTION OF IMPACTED MANDIBULAR 3RD MOLARS IN POPULATION OF JIZAN PROVINCE OF SAUDI ARABIA- A RANDOMISED PROSPECTIVE STUDY”

Ahtesham Ahmad Qurishi*

Department of Maxillofacial Surgery and Diagnostic Sciences College of Dentistry Jizan University Saudi Arabia

Received: 2026-04-08 · Published: 2025-11-19

© 2025 The Author(s) and the original publisher.

CC BY-NC 4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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Original title
COMPARING THE LOCAL ANAESTHETIC EFFICACY DURING THE EXTRACTION OF IMPACTED MANDIBULAR 3RD MOLARS IN POPULATION OF JIZAN PROVINCE OF SAUDI ARABIA- A RANDOMISED PROSPECTIVE STUDY”
Author
Ahtesham Ahmad Qurishi
Source journal
Bulletin of Stomatology and Maxillofacial Surgery
Published
2025-11-19
Licence
Creative Commons Attribution-NonCommercial 4.0 International
Original
https://doi.org/10.58240/1829006X-2025.21.10-408

Abstract

Aim:To compare the local anesthetic efficacy of 2% lidocaine, 2% mepivacaine, and 4% articaine with 1:100,000 epinephrine during the surgical extraction of impacted mandibular third molars in the Jizan population of Saudi Arabia. Materials and Methods:This randomized prospective clinical study included 180 ASA-I patients aged 20–40 years requiring surgical removal of impacted mandibular third molars. Patients were randomly allocated into three groups (n = 60 each): Group A received 2% lidocaine, Group B received 2% mepivacaine, and Group C received 4% articaine, all with 1:100,000 epinephrine. Onset and duration of anesthesia, reinjection requirement, surgical time, hemodynamic changes, return of sensation, and postoperative pain (VAS at 24 hours) were assessed. Data were analyzed using ANOVA with p < 0.05 considered statistically significant. Results:Articaine showed the fastest onset of anesthesia (1.9 ± 0.4 min) compared to mepivacaine (3.1 ± 0.6 min) and lidocaine (3.5 ± 0.8 min; p < 0.001). The duration of anesthesia was significantly longer with articaine (245 ± 12 min) than mepivacaine (185 ± 15 min) and lidocaine (172 ± 14 min; p < 0.001). Reinjection was least required with articaine (4%) compared to mepivacaine (10%) and lidocaine (18%). Surgical time was shortest in the articaine group (18.6 ± 2.3 min; p < 0.05). Postoperative pain scores were lowest with articaine (2.1 ± 0.9) compared to mepivacaine (3.9 ± 1.1) and lidocaine (4.5 ± 1.2; p < 0.001). Hemodynamic variations were minimal and not statistically significant between groups. Conclusion:Articaine provided faster onset, longer duration, superior anesthetic reliability, and lower postoperative pain compared to lidocaine and mepivacaine, without significant hemodynamic risks. It can be considered the anesthetic of choice for surgical removal of impacted mandibular third molars.
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