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    A.L. Torosyan A.L. Torosyan
    Category: Biology
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      Natural Science, Biology, 2025

      DETERMINATION METHOD OF PERMEABILITY COEFFICIENT OF BILAYER LIPID MEMBRANE FOR CATIONIC PORPHYRINS

      A.L. Torosyan A.L. Torosyan
      This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

      © 2025 by author(s) and The Gufo Inc.
      CC BY-NC 4.0 This work is licensed under Creative Commons Attribution–NonCommercial International License (CC BY-NC 4.0).

      Abstract

      In this paper a method is presented for determining the permeability coefficient of bilayer lipid membrane (BLM) for porphyrins by UV/Vis spectrophotometry. BLM is formed on the hole separating two compartments of the cell. The coefficient permeability of BLM is calculated for meso-tetra-[4-N-(2′-hydroxyethyl)pyridyl] porphyrin. The proposed method can be used to determine the permeability coefficient of BLM for other substances.

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