2013; Chemical and Biological Sciences 47 (1 (230): 47–49
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QUANTITATIVE ANALYSIS OF RNA AND ACIDIC PROTEINS OF MONOBLASTS AND MONOCYTES INFECTED WITH AFRICAN SWINE FEVER VIRUS

Hovakim Zakaryan*

Received: 2025-03-12 · Published: 2013-03-10

© 2013 The Author(s) and the original publisher.

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Original title
QUANTITATIVE ANALYSIS OF RNA AND ACIDIC PROTEINS OF MONOBLASTS AND MONOCYTES INFECTED WITH AFRICAN SWINE FEVER VIRUS
Author
Hovakim Zakaryan
Published
2013-03-10
Licence
as stated by the publisher

Abstract

A single cell cytophotometry was used to analyze the amount of RNA and proteins in porcine cells that are susceptible to African Swine Fever Virus (ASFV). The obtained results show that ASFV infection results in depletion of total RNA in the nucleus of monoblasts and monocytes. The level of nuclear acidic proteins in monoblasts is also less, than in control during all time of infection, whereas in monocytes it is higher, than in uninfected cells at the final stage of infection. These data can be used in further researches to elucidate cytopathogenesis of ASFV infection.
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