EFFECT OF 8HzELF EMF AND ITS COMBINATION WITH CISPLATIN ON SARCOMA-180 TISSUE HYDRATION AND OUABAIN BINDING

The modulation effect of 8 Hz(2.5mT)extra low frequency electromagnetic fields (ELF EMF) on cisPt inducedchanges of cell hydration and number of ouabain receptors (Na+/K+-ATPase molecules) in membrane of Sarcoma-180 tissuewas studied. Tissue hydration was measured as wet mass/dry mass and expressed as a water content of g/g in dry mass. The number of 3H-ouabain receptors in membrane was counted by isotope scintillation counter. It was shown, that 8 HzELF EMF has dehydration effect on cancer tissue. Besides, 8 Hz ELF EMF isnot a modulator of cisPt effect on tumor tissue.