2015; Chemical and Biological Sciences 49 (1 (236): 45–49
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EFFECT OF DNA GC-CONTENT ON INTERACTION WITH METHYLENE BLUE

L.A. Hambardzumyan*

Received: 2025-03-10 · Published: 2015-04-01

© 2015 The Author(s) and the original publisher.

Licence: as stated by the publisher.
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Original title
EFFECT OF DNA GC-CONTENT ON INTERACTION WITH METHYLENE BLUE
Author
L.A. Hambardzumyan
Published
2015-04-01
Licence
as stated by the publisher

Abstract

The melting of methylene blue (MB) complexes of DNA with different GC-content sequences at 0.02 M ionic strength of the solution has been carried out. It was shown that the change of melting interval width of MB complexes with DNA increases depending on GC-content enhancement within DNA sequences. It was revealed that MB is bound to DNA by semi-intercalation mode.
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