Bulletin of Stomatology and Maxillofacial Surgery
2025; 59–64
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ENCEPHALITIS MANIFESTATION IN A PATIENT WITH EXPANDED DENGUE SYNDROME

Vembi Rizky Fatmawati*, Usman Hadi

Study program of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia · Tropical Medicine and Infectious Disease Division, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga -RSUD Dr. Soetomo, Surabaya, Indonesia

Received: 2025-09-25 · Published: 2025-08-31

© 2025 The Author(s) and the original publisher.

CC BY-NC 4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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Original title
ENCEPHALITIS MANIFESTATION IN A PATIENT WITH EXPANDED DENGUE SYNDROME
Authors
Vembi Rizky Fatmawati, Usman Hadi
Source journal
Bulletin of Stomatology and Maxillofacial Surgery
Published
2025-08-31
Licence
Creative Commons Attribution-NonCommercial 4.0 International
Original
https://doi.org/10.58240/1829006x-2025.21.8-59

Abstract

The expansion of dengue symptoms to other organs has been known as expanded dengue syndrome. One form of this is encephalitis. An 18-year-old male was reported to have communication disruption for one day, high fever for 4 days, headache, retroorbital pain, and myalgia. Thrombocytopenia, hemoconcentration, NS1, and IgG-IgM dengue were positive in laboratory testing. Brain CT results gyral enhancement on the right and left side frontotemporoparieto-occipital lobe, hypodense area with unclear border on occipital lobe, effacement of sulci and gyri. Dengue hemorrhagic fever and encephalitis were the patient's diagnoses. After five days of therapy, the condition improved. Febrile seizures, intracranial thrombosis/ hemorrhages, encephalopathy, aseptic meningitis/ encephalitis, transverse myelitis, polyneuropathies/ mononeuropathies/ Guillain-Barre Syndrome, and subdural effusions are the neurological signs of expanded dengue infection. CNS involvement reflects severe disease with poorer recovery. A case of encephalitis in a patient with dengue hemorrhagic fever has been reported. Supportive management improves.
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