Abstract
Cerebrospinal fluid (CSF) leakage due to anterior skull base defect is considered a topical issue in otorhinolaryngology and neurosurgery. An abnormal relation between the nasal cavity, the sinuses and the subarachnoid space causes CSF leakage. The clinical manifestations, diagnosis, surgical approaches and results of treatments of two cases, spontaneous and tumor-induced CSF leakage, have been described in this work.