Bulletin of Stomatology and Maxillofacial Surgery
ISSN 1829-006X
2026; 167–179
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ENHANCING SURGICAL HEALING WITH OZONE GEL IN GRAFTLESS CLOSED SINUS LIFT PROCEDURES FOR DENTAL IMPLANTS: A RANDOMIZED CONTROLLED STUDY

Dina Yousry*, Raafat Riad, Rehab Soliman, Mohamed Sholkamy

Oral & Maxillofacial Surgery Department, Faculty of Oral and Dental Medicine, Misr International University, Cairo, Egypt · 2Oral & Maxillofacial Surgery Department, Faculty of Oral and Dental Medicine, Misr International University, Cairo, Egyp · Oral & Maxillofacial Surgery Department, Faculty of Oral and Dental Medicine, Misr International University Cairo, Egypt. · Oral & Maxillofacial Surgery Department, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt

Received: 2026-01-07 · Published: 2026-12-31

© 2026 The Author(s) and the original publisher.

CC BY-NC 4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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Original title
ENHANCING SURGICAL HEALING WITH OZONE GEL IN GRAFTLESS CLOSED SINUS LIFT PROCEDURES FOR DENTAL IMPLANTS: A RANDOMIZED CONTROLLED STUDY
Authors
Dina Yousry, Raafat Riad, Rehab Soliman, Mohamed Sholkamy
Source journal
Bulletin of Stomatology and Maxillofacial Surgery
Published
2026-12-31
Licence
Creative Commons Attribution-NonCommercial 4.0 International
Original
https://doi.org/10.58240/1829006X-2025.21.12-167

Abstract

Objective: This study aims to provide comprehensive evaluation of ozone gel's effects alongside standard postoperative care in effectively reducing pain and improving soft tissue healing after dental implant procedures with closed sinus lifting done simultaneously. Materials and Methods: A total of 30 sinuses with an average residual alveolar bone height ranging from 4-7 mm participated in this clinical trial. Following a closed sinus lift procedure, patients were randomized into two groups: one for the ozone gel recipient group and the other for control group. Pain was rated based on the visual analog scale at 24, 48 hours and one week postoperative; soft tissue healing was rated according to the Landry healing index at seven and 14 days. Data were analyzed using appropriate statistical methods, with a significance value considered at p < 0.05. Results: The ozone therapy group showed a statistically significant reduction in pain scores specifically at 24 hours and 48 hours compared to the control group (p < 0.05). In terms of soft tissue healing, the ozone group demonstrated improved soft tissue healing rates 7 days postoperatively.However at 14 days postoperatively , it was insignificant . Conclusion: Ozone therapy has demonstrated considerable potential as an adjunctive treatment following dental implant surgery, effectively mitigating postoperative pain and facilitating soft tissue healing.
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