IMPACT OF DETOXIFICATION SOLUTIONS ON THE ORAL IMPLANT SURFACE- AN INVITRO STUDY
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(CC BY-NC 4.0).
Abstract
Background: Bacterial plaque has been associated with peri-implant conditions. It has been difficult to remove the
bacteria and their metabolites, including lipopolysaccharides, after these biofilms have formed on the implant surface.
Therefore, the purpose of this study was to evaluate the effectiveness of detoxification solutions on the surface of oral
implants.
Materials and Methods: In the current investigation, a total of 45 implants were employed. Prior to biofilm growth,
the sterile saliva was kept at -20°C until it was required to produce pellicle formation on the implant surfaces. For
detoxification of the surface of the oral implant, all samples have been divided evenly into three groups, Group 1:
Control, Group 2: Immersed in Chlorhexidine gluconate solution, Group 3: Immersed in citric acid solution. Each
implant that was assigned remained 60 and 120 seconds immersed in its respective solution. Following preparation,
implants were examined under a scanning electron microscope. The SPSS Statistics version 21.0 was used to analyse
the data that was gathered. One-way analysis of variance and post-hoc testing were used to assess the impact of
detoxification procedures. Results with a p-value of less than 0.05 were considered statistically significant.
Results: After implants immersed for 60 seconds duration, the maximum biofilms was removed in Citric acid solution
group (1.08±0.01) followed by Chlorhexidine gluconate group (1.22±0.04) and control group (1.98±0.06). There was
a statistically significant difference found between the different detoxification solutions. After implants immersed for
120 seconds duration, the maximum biofilms was removed in Citric acid solution group (1.04±0.06) followed by
Chlorhexidine gluconate group (1.14±0.10) and control group (1.90±0.02). But there was no significant difference
found between the different detoxification solutions.
Conclusion: The present study concluded that the maximum detoxification found in Citric acid solution group
compared to Chlorhexidine gluconate group and control group.