Site logo
Natural Science, Biology, 2024, 14, 67–75
DOI: 10.xxxx/example-doi Special Issue 1(2), 2022 186–1928

INVESTIGATION OF ACIDIC DENATURATION OF ETHIDIUM BROMIDE COMPLEXES WITH DNA

Received N/A; revised N/A; accepted N/A
CC BY-NC 4.0 This work is licensed under Creative Commons Attribution–NonCommercial International License (CC BY-NC 4.0).

In the present work the temperature-induced and the acidic denaturation of ethidium bromide (EtBr) complexes with DNA have been carried out. The curves of helix-coil transition of both DNA and its complexes with EtBr in 0 ≤ r ≤ 0.5 (r = [ligand] / [DNA]) were obtained. It has been shown that with enhancement of EtBr concentration the transition point is shifted to the “high values” for both factors invoking this transition. It was also revealed that EtBr interacts with DNA by several modes being in non protonated and

Subscribe to TheGufo Newsletter​