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Natural Science, Biology, 2024, 14, 67–75
DOI: 10.xxxx/example-doi Special Issue 1(2), 2022 186–1928

MEMBRANOTROPIC EFFECT OFMONTIVIPERA RADDEIAND MACROVIPERA LEBETINA OBTUSAVENOM WITH PHOSPHOLIPASE A2 INHIBITED BY p-BROMOPHENACYL BROMIDE

Received N/A; revised N/A; accepted N/A
CC BY-NC 4.0 This work is licensed under Creative Commons Attribution–NonCommercial International License (CC BY-NC 4.0).

In the article influence of Montivipera raddei and Macrovipera lebetina obtusa venom including phospholipase A2 (PLA2) inhibited by p-bromophenacyl bromide on giant unilamellar vesicles, visualized with 8-anilino-1-naphthalenesulfonic acid fluorescence probe, was investigated. The results have shown that both venoms even without the PLA2 activity have a noticeable membranotropic effect on the artificial membranes, but in different ways, so one can propose that investigated viper venoms can contain different PLA2 isomers.

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