2015; Chemical and Biological Sciences 49 (3 (238): 47–52
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MEMBRANOTROPIC EFFECT OFMONTIVIPERA RADDEIAND MACROVIPERA LEBETINA OBTUSAVENOM WITH PHOSPHOLIPASE A2 INHIBITED BY p-BROMOPHENACYL BROMIDE

Lusine Ghulikyan*

Received: 2025-03-10 · Published: 2015-11-20

© 2015 The Author(s) and the original publisher.

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Original title
MEMBRANOTROPIC EFFECT OFMONTIVIPERA RADDEIAND MACROVIPERA LEBETINA OBTUSAVENOM WITH PHOSPHOLIPASE A2 INHIBITED BY p-BROMOPHENACYL BROMIDE
Author
Lusine Ghulikyan
Published
2015-11-20
Licence
as stated by the publisher

Abstract

In the article influence of Montivipera raddei and Macrovipera lebetina obtusa venom including phospholipase A2 (PLA2) inhibited by p-bromophenacyl bromide on giant unilamellar vesicles, visualized with 8-anilino-1-naphthalenesulfonic acid fluorescence probe, was investigated. The results have shown that both venoms even without the PLA2 activity have a noticeable membranotropic effect on the artificial membranes, but in different ways, so one can propose that investigated viper venoms can contain different PLA2 isomers.
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