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Natural Sciences, Stomotology, 2026

METASTATIC CANCERS TO THE ORAL CAVITY: AN OVERVIEW

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Submitted: 2026-05-11
CC BY-NC 4.0 This work is licensed under Creative Commons Attribution–NonCommercial International License (CC BY-NC 4.0).

Abstract

Metastasis is a complex biological process that begins when cancer cells separate from the original tumor and spread to other tissues and organs, causing morbidity and death. Metastatic cancers to the oral cavity are rare and frequently associated with widespread disease. The diagnosis of these tumors is challenging, and their prognosis is poor. The purpose of this paper is to review the pathogenesis, clinical and histological features, treatment options, and prognosis of metastatic cancers that affect the oral cavity.

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