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The influence of synthetic amino acids and peptides on the growth of Pseudomonas aeruginosa multidrug resistant strains isolated from soil has been studied. All investigated strains were sensitive to (S)-β-[4-allyl-3-(furan-2-yl)-5- -thioxo-1,2,4-triasol-1-yl]-α-alanine, (S)-β-[4-allyl-3-(2’-chlorophenyl)-5-thioxo-1,2,4-triazol-1-yl]-α-alanine, dipeptide N-formyl-methionyl-(S)-β-[4-allyl-3-(2’-chlorophenyl)-5-thioxo-1,2,4-triasol-1-yl]-α-alanine and tripeptide alanyl-glycyl-(S)-β-[4-allyl-3-(pyridin-4’-yl)-5-thioxo-1,2,4-triasol-1-yl]-α-alanine. Dipeptide alanyl-(S)-β-[4-allyl-3-(pyridin-4’-yl)-5-thioxo-1,2,4-triazol-1-yl]-α-alanine demonstrates the strongest effect on the growth of P. aeruginosa strains 9311 (resistant to beta-lactams) and 9211 (resistant to beta-lactams and chloramphenicol), but has no influence on the P. aeruginosa 5249 (resistant to all antibiotics used in this study).