THE APPLICATION OF AN ENAMEL MATRIX PROTEIN (EMDOGAIN) IN REGENERATIVE PERIODONTAL THERAPY. CLINICAL SERIES

Objectives: The purpose of this clinical series is to present indications for regenerative therapy with EMD. Materials and Methods: The study included 53 patients with osseous defects from 7-15mm’s in depth. Each patient understood that the procedures were not within the normal treatment due to the severity of the defects but opted to accept treatment. Along with EMD each defect also had freeze fried demineralized bone placed in the defect as well. Results: Reentry of the original defects was undertaken at approximately 1 year after surgery. It was noted that for the most part significant improvement was noted in almost all defects. Exact improvement of defects was not calculated. In several cases 10-year reentry was undertaken and in fact further reduction in defects were noted. It could not be determined at any time over the 10-year period that the reduction in pocket depth was in fact bone as no histology was ever taken to verify what the defects were filled with. Conclusions: Clinical studies have indicated that treatment with EMD with freeze dried demineralized bone positively influences regenerative periodontal therapy.