Bulletin of Stomatology and Maxillofacial Surgery
ISSN 1829-006X
2025; 67–72
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THE EFFECTIVENESS OF TRIAMCINOLONE ACETONIDE (0.1%), AMLEXANOX (5%) AND CLOBETASOL PROPIONATE (0.05%) IN TREATING ORAL LICHEN PLANUS

Richa Goel*

Received: 2026-04-08 · Published: 2025-09-24

© 2025 The Author(s) and the original publisher.

CC BY-NC 4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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Original title
THE EFFECTIVENESS OF TRIAMCINOLONE ACETONIDE (0.1%), AMLEXANOX (5%) AND CLOBETASOL PROPIONATE (0.05%) IN TREATING ORAL LICHEN PLANUS
Author
Richa Goel
Source journal
Bulletin of Stomatology and Maxillofacial Surgery
Published
2025-09-24
Licence
Creative Commons Attribution-NonCommercial 4.0 International
Original
https://doi.org/10.58240/1829006X-2025.21.9-67

Abstract

Background: Oral lichen planus (OLP) is a potentially malignant mucocutaneous condition. The present research done was to evaluate the efficiency of 0.1% triamcinolone acetonide, 0.05% clobetasol propionate, and 5% amlexanox in treating OLP. Methods: Three equal groups of sixty participants with OLP were treated with topical medications: 5% amlexanox (Group III), 0.1% triamcinolone acetonide (Group II), and 0.05% clobetasol propionate (Group I). The visual analogue scale (VAS) was used to evaluate the patients' level of pain. On Days 1, 7, and 15 of the trial, their erosive area and ulcerative lesion type were also assessed. Results: In every investigated group, the VAS pain scale score decreased statistically significantly between Day 1 and Day 15. In comparison to the other two groups, Group B's pain score was lower. Additionally, on the fifteenth day, the erosive region on the left and right buccal mucosaon decreased with all three of the studied medications. In comparison to 0.05% Clobetasol Propionate and 5% Amlexanox, triamcinolone acetonide (0.1%) was efficient in improving the erosive lesions on the buccal mucosa on the right and left sides. Of the three groups, Group II had the highest healing ratio (37 cases), Group I had the second-highest (32 cases), and Group III had the lowest (30 cases). Conclusion: All medicines utilised in this trial –triamcinolone acetonide, clobetasolpropionate andamlexanox–were beneficial in managing OLP patients; consequently, it can be considered as substitute.
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