Bulletin of Stomatology and Maxillofacial Surgery
ISSN 1829-006X
2025; 76–80
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USE OF STEROIDS AND STEROID-SPARING TOPICAL THERAPIES IN MANAGEMENT OF IMMUNOLOGICALLY MEDIATED ORAL MUCOSAL LESIONS REPORTED IN A PRIVATE DENTAL INSTITUTION- A RETROSPECTIVE STUDY

Sharan Mann*, T. N. Uma Maheswari, Ankita Bohra

Saveetha University · Saveetha Institute of Medical and Technical Sciences (SIMATS)

Received: 2026-04-08 · Published: 2025-12-05

© 2025 The Author(s) and the original publisher.

CC BY-NC 4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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Original title
USE OF STEROIDS AND STEROID-SPARING TOPICAL THERAPIES IN MANAGEMENT OF IMMUNOLOGICALLY MEDIATED ORAL MUCOSAL LESIONS REPORTED IN A PRIVATE DENTAL INSTITUTION- A RETROSPECTIVE STUDY
Authors
Sharan Mann, T. N. Uma Maheswari, Ankita Bohra
Source journal
Bulletin of Stomatology and Maxillofacial Surgery
Published
2025-12-05
Licence
Creative Commons Attribution-NonCommercial 4.0 International
Original
https://doi.org/10.58240/1829006X-2025.21.11-76

Abstract

Aim: This study aimed to evaluate the efficacy and safety of steroid and steroid-sparing topical therapies in managing immunologically mediated oral mucosal lesions in a private dental institution. Materials and Methods: A retrospective study was conducted at a private dental college in Chennai, analysing cases from January 2019 to December 2023. The study included patients aged 20 to 85 years diagnosed with pemphigus, pemphigoid, lichen planus, erythema multiforme, and recurrent aphthous ulcers. Data were extracted from the Dental Information Archiving System (DIAS) and analysed using descriptive statistics. Results: Lichen planus was the most prevalent condition, accounting for 66.23% of cases, followed by aphthous ulcers with 27.88%. Triamcinolone acetonide was the most commonly prescribed steroid (55.83%), while Tacrolimus was the most frequently used non-steroidal agent (59.69%). Steroid-sparing therapies showed significant advantages in reducing adverse effects compared to traditional steroids. Conclusion: The study highlights a preference for potent steroids like Triamcinolone acetonide, while the emerging use of steroid-sparing agents, especially Tacrolimus, suggests a shift toward safer, long-term treatments. Further clinical trials are needed to establish optimal protocols for managing immunologically mediated oral mucosal lesions
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