2017; Chemical and Biological Sciences 51 (2 (243): 81–87
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3-(PROP-2-YNYL)DIHYDROFURAN-2(3H)-ONES: SYNTHONES FOR LACTONE-CONTAINING NEW COMPOUNDS

A.S. Galstyan*

Received: 2025-03-07 · Published: 2017-06-13

© 2017 The Author(s) and the original publisher.

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Original title
3-(PROP-2-YNYL)DIHYDROFURAN-2(3H)-ONES: SYNTHONES FOR LACTONE-CONTAINING NEW COMPOUNDS
Author
A.S. Galstyan
Published
2017-06-13
Licence
as stated by the publisher

Abstract

The behavior of 5,5-disubstituted-3-(prop-2-ynyl)dihydrofuran-2(3H)-ones under conditions of Mannich and coupling reactions have been studied. It was established that their interaction with paraform and secondary amines in the presence of copper halogenides (I) afforded aminobutynyl derivatives of γ-lactones, and the coupling reactions with active halogenides resulted in butynalkynyl derivatives. Synthesized compounds are representatives of new systems earlier not described in the literature.
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