2023; Chemical and Biological Sciences 57 (2 (261): 68–76
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A NEW METHOD FOR THE PREPARATION OF HYDRAZIDES OF SUBSTITUTED GAMMA-HYDROXYBUTANOIC ACIDS

Tariel V. Ghochikyan*, Armen S. Galstyan, Melanya Samvelyan

Received: 2025-03-03 · Published: 2023-05-03

© 2023 The Author(s) and the original publisher.

CC BY-NC 4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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Original title
A NEW METHOD FOR THE PREPARATION OF HYDRAZIDES OF SUBSTITUTED GAMMA-HYDROXYBUTANOIC ACIDS
Authors
Tariel V. Ghochikyan, Armen S. Galstyan, Melanya Samvelyan
Published
2023-05-03
Licence
Creative Commons Attribution-NonCommercial 4.0 International
Original
https://doi.org/10.46991/PYSU:B/2023.57.2.068

Abstract

A method providing a high yield (80–94%) for producing gamma-hydroxy-butanoic acids hydrazides by the interaction of various representatives of cyclic esters with 85% hydrazine hydrate has been elaborated. It has been established that the introduction of a gamma-hydroxypropyl residue into the hydrazides composition results in new biological properties.
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