2013; Physical and Mathematical Sciences, 47(2 (231): 50–57
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ADSORPTION OF SHORT LIGANDS ON DNA WITH MODIFICATION OF ADSORPTION CENTER STRUCTURE

V. Arakelyan=*

Received: 2025-02-17 · Published: 2013-06-20

© 2013 The Author(s) and the original publisher.

CC BY 4.0 This work is licensed under a Creative Commons Attribution 4.0 International License.
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Original title
ADSORPTION OF SHORT LIGANDS ON DNA WITH MODIFICATION OF ADSORPTION CENTER STRUCTURE
Author
V. Arakelyan=
Published
2013-06-20
Licence
Creative Commons Attribution 4.0 International

Abstract

The reversible adsorption of short ligands on DNA at arbitrary filling has been theoretically investigated, the kinetics of adsorption of ligands on DNA being described in a self-consistent way with the modified structure of an adsorbing center. The case when one adsorbed ligand occupied two adsorption centers on DNA was considered. It was shown that an allowance for the modification of the potential well of the adsorbing center led to the possibility of realizing various regimes of adsorption.
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